Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease.

Alana V Beadell,Zhou Zhang,Ana W Capuano,David A Bennett,Chuan He,Wei Zhang,Zoe Arvanitakis

Journal of Alzheimer's disease : JAD（2023）

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摘要

We demonstrate in this small sample the feasibility of detecting and characterizing 5hmC in DM-associated AD and of using 5hmC information contained in circulating cfDNA to detect AD in high-risk individuals, such as those with diabetes.

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关键词

diabetes mellitus,alzheimers,genome-wide

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