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A Bi-Endpoint Expectation-Maximisation Algorithm for Re-Estimating Sample Size for the Time-to-event Endpoint under the Blind Condition

Longshen Xie,Hui Lu

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS(2024)

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Key words
adaptive design,blinded sample size re-estimation,EM algorithm,interim analysis,time-to-event endpoint
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