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Structural study of wild-type and phospho-mimic XRCC4 dimer and multimer proteins using circular dichroism spectroscopy.

Kai Nishikubo,Maho Hasegawa,Yudai Izumi,Kentaro Fujii,Koichi Matsuo,Yoshihisa Matsumoto,Akinari Yokoya

International journal of radiation biology（2023）

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Abstract
An increase in the β-strand content in XRCC4 is essential for stabilization of the multimeric form through C-terminal phosphorylation, allowing formation of the large double-strand break repair machinery.
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Key words
multimer proteins,wild-type,phospho-mimic
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