Heterogeneity of Treatment Effects by Predicted Risk in Pulmonary Arterial Hypertension: An Individual Participant Data Meta-analysis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE(2023)
Abstract
We found that predicted risk of one-year mortality in PAH modified treatment effect as measured by 6MWD, but not clinical worsening. Our findings highlight the importance of identifying sources of treatment heterogeneity by predicted risk to tailor studies to patients most likely to have the greatest treatment response.
MoreTranslated text
Key words
pulmonary arterial hypertension,treatment effects
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined