Terminal fucosylation of haptoglobin in cancer-derived exosomes during cholangiocarcinoma progression.

Frontiers in oncology(2023)

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摘要
This study suggests that terminal fucosylation of Hp in cancer-derived exosomes can be a novel glycan marker for diagnosis and prognosis of CCA. These findings highlight the potential of glycan analysis in different fractions of serum for biomarker discover for other diseases. Further research is needed to understand the role of fucosylated EVs on CCA progression.
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terminal fucosylation,exosomes,cholangiocarcinoma,haptoglobin,cancer-derived
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