Cancer gene analysis of liquid-based cytology specimens using next-generation sequencing: A technical report of bimodal DNA- and RNA-based panel application.

Toshiaki Akahane,Tomomi Isochi-Yamaguchi,Natumi Hashiba-Ohnuki,Nobuyuki Bandoh,Eriko Aimono,Yasutaka Kato,Hiroshi Nishihara,Hajime Kamada,Akihide Tanimoto

Diagnostic cytopathology（2023）

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摘要

Simultaneous application of bimodal DNA- and RNA-based gene panels was useful in NGS analysis using residual LBC specimens for integrative diagnosis. Residual LBC specimens for genomic analysis, including fusion gene analysis, are particularly useful for obtaining genomic information before surgical resection.

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关键词

bimodal DNA and RNA panel, carcinoma, liquid-based cytology, next-generation sequencing, salivary gland, thyroid gland

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