Systematic review and Meta-analysis of the Role of total Pancreatectomy as an Alternative to Pancreatoduodenectomy in Patients at High Risk for Postoperative Pancreatic Fistula: is it a Justifiable Indication?

Thomas F Stoop,Erik Bergquist, Rutger T Theijse,Sebastian Hempel,Susan van Dieren,Ernesto Sparrelid,Marius Distler,Thilo Hackert,Marc G Besselink,Marco Del Chiaro,Poya Ghorbani

Annals of surgery（2023）

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Abstract

This systematic review and meta-analysis found no reduction in short-term mortality and major morbidity after TP as compared to PD in patients at high-risk for POPF. However, if TP is used as a bail-out procedure, the comparable long-term quality of life is reassuring.

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Key words

postoperative pancreatic fistula,total pancreatectomy,pancreatoduodenectomy,systematic review,meta-analysis

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