Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study.

A I Lokki,Z Ren,M Triebwasser,E Daly,M Perola,K Auro,R Burwick,J E Salmon,M Daly,H Laivuori,J P Atkinson,A Java, S Meri

BJOG : an international journal of obstetrics and gynaecology（2023）

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摘要

These results suggest that complement dysregulation due to mutations in complement factor H is among the pathophysiological mechanisms underlying severe pre-eclampsia.

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关键词

complement system, factor H, genetics, pre-eclampsia, basic science

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