Predictors of premature termination and completion of randomized controlled trials.

Giovanni J Soletti,Katia Audisio,Gianmarco Cancelli,Mohammed Rahouma,Arnaldo Dimagli,Lamia Harik,Roberto Perezgrovas Olaria,Talal Alzghari, Kevin R An,Hillary Polk,Hillary Lia,Derrick Y Tam,Stephen E Fremes,Mario Gaudino

Contemporary clinical trials（2023）

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Abstract

Randomized clinical trials (RCTs) have a key role in progressing biomedical research and guiding clinical decision making, but premature termination remains high (up to 30%), raising concerns regarding funding expenditure and resource allocation. This brief report sought to identify variables associated with RCTs' premature termination and completion.

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Key words

premature termination,trials,completion

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