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MicroRNA-646 inhibits the proliferation of ovarian granulosa cells via insulin-like growth factor 1 (IGF-1) in polycystic ovarian syndrome (PCOS).

Jiali Lu,Feilan Xuan,Aixue Chen,Ruiying Jin,Weimei Zhou,Yongju Ye,Yuefang Ren

Endokrynologia Polska（2023）

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Abstract
MiR-646 inhibitor treatment can promote the proliferation of GCs by regulating the cell cycle and inhibiting apoptosis, while silenced-IGF-1 antagonizes it.
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polycystic ovarian syndrome, granulosa cells, microRNA, miR-646, IGF1, KGN cells
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