Critical Role of the cGAS-STING Pathway in Doxorubicin-Induced Cardiotoxicity.

Circulation research（2023）

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摘要

Our findings indicate a critical role of the cardiac EC cGAS-STING pathway in DIC. The cGAS-STING pathway may represent a novel therapeutic target for preventing DIC.

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关键词

cardiotoxicity, doxorubicin, endothelial cells, mitochondria, NAD

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