Corrigendum to “Menopausal symptoms in the Southwest United States: A cross-sectional survey of women from areas with different socioeconomic resources” [Maturitas, volume 154, December 2021, pages 7–12]

Maturitas(2023)

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The authors regret that we report using a score range of 0–3 for the Greene Climacteric Scale (GCS), but the calculations were done using a range of 1–4. We have updated our analyses and data, and confirm that most of the relationships reported remain, although there are some changes. We believe the overall message reported remains. The following points in our original article are corrected:-Results in the Abstract: “Multivariate analysis revealed higher total GCS scores in the Phoenix vs. Scottsdale cohort (39.13 vs 30.14, p < 0.001), which was also seen in the psychological and somatic domains, as well as the anxiety and depression subdomains.” is corrected to “Multivariate analysis revealed higher total GCS scores in the Phoenix vs. Scottsdale cohort (17.69 vs. 11.69, p = 0.0005), which was also seen in the psychological and somatic domains, as well as the depression subdomain.”-2.3 Statistical analysis “Participant demographics and reproductive health responses were reported as mean (SD), or as frequency and percentage. Mean (SD) total GCS scores were calculated from the sum of all 21 questions divided by the number of participants in each group”. is corrected to: “Participant demographics and reproductive health responses were reported as mean (SD), or as frequency and percentage. Mean (SD) total GCS scores were calculated from the sum of all 21 questions divided by the number of participants in each location”.-3.2. Frequently reported symptoms in each cohort: “In the Scottsdale cohort, the most frequently reported symptoms were feeling tired or lacking in energy (78%), difficulty sleeping (68.2%), and irritability (68.6%). Fifteen out of the 21 symptoms in the GCS questionnaire were significantly more bothersome in the Phoenix cohort compared to the Scottsdale cohort based on mean scores.” is corrected to: “In the Scottsdale cohort, the most frequently reported symptoms were feeling tired or lacking in energy (79.4%), loss of interest in sex (75.4%) and difficulty sleeping or sweating at night (70.9%). Thirteen out of the 21 symptoms in the GCS questionnaire were significantly more bothersome in the Phoenix cohort compared to the Scottsdale cohort based on mean scores.”-3.3. GCS scores, univariate and multivariate analyses: “Total GCS scores were found to be higher in the Phoenix cohort, indicating more symptoms compared to the Scottsdale cohort in the univariate analysis (40.9 ±15.19 vs 30.6 ±6.63, p<0.001). This relationship was also seen by domain in the psychological (21.5 ±8.65 vs 17.7 ±4.88, p<0.001), and somatic domains (13.8 ±6.08 vs 9.6 ±2.52, p<0.001), as well as in the depression subdomain 11.5 ±4.79 vs 8.1 ±2.55, p<0.001). No statistically significant differences were seen for the vasomotor domain (3.8 ±1.98 vs 3.6 ±1.34, p=0.350), sexual dysfunction domain (1.9 ±1.02 vs 1.7 ±0.79, p=0.225) or the anxiety subdomain (10.0 ±4.36 vs 9.6 ±2.88, p=0.423).” is corrected to: “Total GCS scores were found to be higher in the Phoenix cohort, indicating more symptoms compared to the Scottsdale cohort in the univariate analysis (19.8 ± 15.31 vs 13.2 ± 8.58, p < 0.001). This relationship was also seen by domain in the psychological (10.4 ± 8.74 vs 8.1 ± 5.94; p = 0.04), and somatic domains (6.8 ± 6.08 vs 3.0 ± 2.8; p<0.001) as well as in the depression (5.4 ± 4.8 vs 3.7 ± 2.96; p = 0.006) and sexual dysfunction domain (0.9 ± 1.02 vs 0.5 ± 1.24; p = 0.017). No statistically significant differences were seen for the vasomotor domain (1.8 ± 1.98 vs 2.1 ± 1.71; p = 0.353), or the anxiety subdomain (5.0 ± 4.36 vs 4.4 ± 3.41; p = 0.278).” “In multivariable models adjusting for age, race, menopause stage, and HT use, the same relationships were noted, with significantly higher scores in the Phoenix cohort compared to the Scottsdale cohort in the total GCS score, psychological and somatic domains, as well as the depression subdomain. Additionally, women in the Phoenix group had significantly higher anxiety subdomain scores compared to Scottsdale post-adjustment (Table 4 and Fig. 1).” is corrected to: “In multivariable models adjusting for age, race, menopause stage, and HT use, the same relationships were noted, with significantly higher scores in the Phoenix cohort compared to the Scottsdale cohort in the total GCS score, psychological and somatic domains, as well as the depression subdomain, but not for the sexual dysfunction domain (Table 4 and Fig. 1).” (Note: the difference in the scores for sexual dysfunction was statistically significant when unadjusted but not after adjustment, both here and as originally reported.) Discussion “Total, somatic and psychological symptom burden, including self-reported depression and anxiety were significantly higher in the uninsured/homeless and predominantly Hispanic women living in the area of lower neighborhood advantage compared to the insured women living in an area of higher neighborhood advantage, even after accounting for the influence of race, age, and use of HT.” is corrected to: “Total, somatic and psychological symptom burden, including self-reported depression were significantly higher in the uninsured/homeless and predominantly Hispanic women living in the area of lower neighborhood advantage compared to the insured women living in an area of higher neighborhood advantage, even after accounting for the influence of race, age, and use of HT.”-The corrected Table 3 is presented in full below.Table 3.Menopause Symptom Descriptive Statistics: Mean symptom bother scores with frequency of women experiencing each symptom (a little, quite a bit, or extremely).Phoenix(N = 104)Mean ± SD (%)Scottsdale(N = 151)Mean ± SD (%)p-valueHeart beating quickly or strongly0.7 ± 0.84 (48.3 %)0.5 ± 0.70 (36.9 %)0.068Feeling tense or nervous1.1 ± 1.04 (65.6 %)0.8 ± 0.77 (63.6 %)0.024Difficulty in sleeping1.2 ± 1.02 (69.6 %)1.1 ± 0.93 (70.9 %)0.607Excitable0.8 ± 1.04 (46.0 %)0.6 ± 0.74 (47.5 %)0.09Attacks of anxiety, panic0.8 ± 1.04 (46.7 %)0.4 ± 0.66 (34.3 %)<0.001Difficulty in concentrating0.9 ± 1.02 (56.2 %)1.0 ± 0.82 (67.9 %)0.849Feeling tired or lacking in energy1.4 ± 0.98 (81.5 %)1.2 ± 0.84 (79.4 %)0.11Loss of interest in most things0.9 ± 1.05 (55.6 %)0.6 ± 0.80 (44.0 %)0.012Feeling unhappy or depressed1.1 ± 1.13 (58.2 %)0.7 ± 0.75 (52.5 %)0.001Crying spells0.9 ± 1.11 (50.5 %)0.5 ± 0.84 (31.8 %)0.001Irritability1.0 ± 0.97 (62.2 %)0.9 ± 0.74 (69.0 %)0.622Feeling dizzy or faint0.8 ± 0.86 (53.9 %)0.3 ± 0.58 (21.3 %)<0.001Pressure or tightness in head or body0.9 ± 1.03 (54.4 %)0.3 ± 0.62 (22.9 %)<0.001Parts of body feel numb or tingling1.0 ± 1.03 (57.8 %)0.5 ± 0.67 (38.7 %)<0.001Headaches1.2 ± 0.97 (71.1 %)0.7 ± 0.81 (51.1 %)<0.001Muscle and joint pains1.4 ± 1.08 (75.8 %)0.9 ± 0.89 (58.9 %)<0.001Loss of feeling in hands or feet0.8 ± 1.13 (40.0 %)0.2 ± 0.59 (17.7 %)<0.001Breathing difficulties0.8 ± 1.04 (45.6 %)0.3 ± 0.8 (20.5 %)<0.001Hot flushes0.8 ± 0.95 (50.5 %)1.0 ± 0.93 (62.4 %)0.221Sweating at night1.0 ± 1.05 (56.7 %)1.1 ± 0.94 (70.9 %)0.363Loss of interest in sex0.9 ± 1.02 (53.3 %)1.3 ± 1.01 (75.4 %)0.002 Open table in a new tab Missing values not reported in table.-The corrected Table 4 is presented in full below.Table 4.Participant GCS Symptom Bother Scores by Domain and Subdomain.Phoenix(N = 104)Scottsdale(N = 151)p-valueGreen Climacteric Scale score: Mean (95 % CI)Total17.69 (14.94–21.03)11.69 (0.67–12.83)0.0005Somatic domain6.07 (4.96–7.38)3.2 (2.86–3.57)<0.0001Psychological domain9.66 (8.11–11.63)7.17 (6.45–7.93)0.0019Vasomotor domain2.69 (2.33–3.10)2.31 (2.13–2.5)0.1655Anxiety subdomain4.83 (4.12–5.65)4.28 (3.88–4.69)0.0844Depression subdomain6.18 (5.3–7.32)3.62 (3.29–3.96)<0.0001Sexual dysfunction domain1.49 (1.34–1.67)1.58 (1.48–1.69)0.7858 Open table in a new tab Scores are adjusted for age, hormone therapy, menopause group and race. Missing values not reported in table.-The corrected Fig. 1 is presented below. The authors would like to apologise for any inconvenience caused. Menopausal symptoms in the Southwest United States: A cross-sectional survey of women from areas with different socioeconomic resourcesMaturitasVol. 154PreviewMenopause is a time of transition in a woman's life, and can be accompanied by distressing symptoms including vasomotor symptoms or “hot flashes”, changes in mood, loss of libido, impaired sleep, increased fatigue, and vaginal atrophy or dryness [1]. Women from different geographies and from ethnically diverse populations report different menopausal symptom frequency and characteristics, which may be partially explained by regional and geographical differences [2]. Prior studies have evaluated how socioeconomic influences may impact the age of menopause, and have demonstrated that lower education and occupation levels, lower household income level, and having no partner, may result in an earlier age at onset of natural menopause [3–5]. Full-Text PDF
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menopausal symptoms,southwest united states,women,cross-sectional
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