Increased prevalence of nodular thyroid disease in patients with Klinefelter syndrome.

Rosa di Fraia,Daniela Esposito,Lucia Digitale Selvaggio,Francesca Allosso,Roberto Alfano,Mario Rotondi,Giancarlo Balercia,Giacomo Accardo,Daniela Pasquali

Endocrine（2023）

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摘要

We observed a significantly higher prevalence of nodular thyroid disease in KS compared to the control group. The increase in nodular thyroid disease is likely linked to low levels of FT4, inappropriate TSH secretion, and/or genetic instability.

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关键词

Thyroid, Thyroid nodules, Klinefelter syndrome, Hashimoto's thyroiditis, 47, XXY

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