Patients undergoing primary, cementless TKA had similar pain, opioid utilization, and functional outcomes compared to matched patients with cemented fixation.

The cemented and cementless cohorts had similar lowest (0.09 vs 0.08), highest (7.36 vs 7.34), and average (3.26 vs 3.27) pain scores using numeric rating scale (P>0.05). They received similar in-hospital (90 vs 102, P=0.176), discharge (315 vs 315, P=0.483), and total (687 vs 720, P=0.547) MMEs. They had similar average inpatient hourly opioid consumption (2.5 vs 2.5 MMEs/hour, P=0.965). Average refills 90-days postoperatively were similar in both cohorts (1.5 vs 1.4 refills, p=0.893). Also, preoperative, 6-week, 3-month, delta 6-week, and delta 3-month PROMs scores were similar between cemented and cementless cohorts (p>0.05) DISCUSSION: This matched study demonstrated similar in-hospital pain scores and opioid utilization, total MMEs prescribed within 90 days, and PROMs at 6 weeks and 3 months postoperatively between cemented and cementless TKAs.