Dysmetabolism-related early sensory Deficits and their Relationship with peripheral Neuropathy Development.

Dimitrios Tsilingiris,Lukas Schimpfle,Ekaterina von Rauchhaupt,Alba Sulaj,Lukas Seebauer,Hannelore Bartl,Stephan Herzig,Julia Szendroedi,Stefan Kopf,Ζoltan Κender

The Journal of clinical endocrinology and metabolism（2023）

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摘要

We demonstrate for the first time the utility of a standardized QST-based approach in identifying early sensory deficits in individuals with and without T2DM. These are associated with a dysmetabolic status signified by IR markers, MetS and higher AGEs which in turn are shown to influence PN development.

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关键词

advanced glycation end products, diabetic polyneuropathy, early neuropathy, insulin resistance, metabolic syndrome, quantitative sensory testing

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