Maternal intake of folate and folic acid during pregnancy and pubertal timing in girls and boys: A population-based cohort study.

Anne Gaml-Sørensen,Nis Brix,Lea Lykke Harrits Lunddorf,Andreas Ernst,Birgit Bjerre Høyer,Sjurdur Frodi Olsen,Charlotta Granström,Gunnar Toft,Tine Brink Henriksen,Cecilia Høst Ramlau-Hansen

Paediatric and perinatal epidemiology（2023）

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摘要

Prenatal exposure to low maternal intake of total folate in mid-pregnancy was not associated with pubertal timing in girls but associated with slightly later pubertal timing in boys. This minor delay is likely not of clinical importance.

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关键词

folate, folic acid, micronutrients, pregnancy exposure, prenatal exposure, reproductive development

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