Impact of cytomegalovirus immunodominant HLA-I donor-recipient matching on the incidence and features of virus DNAemia and virus-specific T-cell immune reconstitution in unmanipulated haploidentical hematopoietic stem cell transplantation.

Dixie Huntley,Estela Giménez,Lourdes Vázquez,María Jesús Pascual,Paula Amat,María José Remigia, Juan Carlos Hernández-Boluda,Magdalena García,Beatriz Gago,Ignacio Torres,Carlos Solano de la Asunción,Rafael Hernani,Ariadna Pérez,Eliseo Albert,José Luis Piñana,Carlos Solano,David Navarro

Transplant infectious disease : an official journal of the Transplantation Society（2023）

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摘要

CMV ID HLA-I matching may impact on the magnitude of CMV-pp65/IE-1-specific CD8 T-cell reconstitution; yet, this effect seemed not to have an impact on the incidence of initial, recurrent CMV DNAemia, or cs-CMVi.

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关键词

hematopoietic stem t‐cell transplantation,cytomegalovirus dnaemia,immune reconstitution,stem t‐cell

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