Geometric learning and statistical modeling for surgical outcomes evaluation in craniosynostosis using 3D photogrammetry

•3D photogrammetry is a popular and safe modality to evaluate craniofacial anomalies.•Deep learning methods can accurately detect craniofacial landmarks in 3D photogrammetry.•Our fully automated framework enables real time evaluation of head shape in clinical settings.•This framework can evaluate patient outcomes before and after surgical intervention.•Corrective surgery for craniosynostosis results in less abnormal head shapes.