Dysprosium particles decorated Ambroxol imprinted polymer sensor to detect carbide-treated mango

In this study, an important mucolytic agent Ambroxol (AMB) has been identified as an artificial ripening marker (ARM) of Himsagar mango. A rare earth dysprosium oxide decorated polyacrylamide cross-linked AMB-imprinted sensor (Dy2O3 @AMB-IP) has been developed. The AMB-IP has been characterized using Fourier transform infrared (FTIR) spectroscopy, and Field emission scanning electron microscopy (FESEM). Carried out to study its analytical performance (buffer variation, scan rate variation). Also, the sensing characteristics (repeatability, reproducibility, stability, selectivity) of the sensor have been studied using differential pulse voltammetry. Novel biomimetic recognition by imprinted polymer has been tailor-made to selectively detect AMB using a voltammetry study. The sensor is repeatable and reproducible with a relative standard deviation of 1.16%, and 0.71%, respectively. Also, it beholds a wide linear detection range (10 μM – 500 μM) with a limit of detection of 6.48 μM/L. Finally, the response of the sensor was correlated to high-resolution liquid chromatography/ mass spectrometry results of Himsagar mango and showed satisfactory results with a correlation factor of 0.99.