Evaluation of alpha-glucosidase inhibition activity and glycosides in the Syringa pubescens Turcz from different geographical origin

•The α-glucosidase inhibitory activity of Syringa pubescens Turcz (SP) extract was firstly assessed in vitro.•Quantitative analysis of six glycosides including salidroside, echinacoisde, forsythoside B, verbascoside, isoacteoside and oleuropein was firstly established and validated for simultaneous determination of six glycosides.•The evaluation of α-glucosidase inhibitory activity of six glycosides was performed. And docking study was conducted to predict the possible binding sites of forsythoside B.