Actinic cheilitis: a clinicopathological retrospective analysis of 110 cases

OBJECTIVE To characterize actinic cheilitis in a sample of patients from a single Brazilian institution. STUDY DESIGN The records were retrospectively reviewed for all actinic cheilitis cases diagnosed from 1995 to 2019. The sociodemographic variables (age, sex, race), topographic aspects, and histopathological features were collected. RESULTS This study evaluated 110 patients, including 90 (81.82%) males, with a mean age of 61.43 years. Clinically, the lesions mainly appeared as plaques (48.18%). All slides were reviewed, with moderate epithelial dysplasia being the most frequent (41.94%), followed by mild (20.16%), severe (14.52%), and no dysplasia (8.87%). Fourteen cases were diagnosed as micro-invasive carcinoma (11.29%) and 4 cases as SCC (3.23%) CONCLUSION The present study showed that most cases presented significant histological alterations, including epithelial dysplasia, micro-invasive carcinoma, and carcinoma, thus proving the importance of clinical and histological evaluations of actinic cheilitis. To characterize actinic cheilitis in a sample of patients from a single Brazilian institution. The records were retrospectively reviewed for all actinic cheilitis cases diagnosed from 1995 to 2019. The sociodemographic variables (age, sex, race), topographic aspects, and histopathological features were collected. This study evaluated 110 patients, including 90 (81.82%) males, with a mean age of 61.43 years. Clinically, the lesions mainly appeared as plaques (48.18%). All slides were reviewed, with moderate epithelial dysplasia being the most frequent (41.94%), followed by mild (20.16%), severe (14.52%), and no dysplasia (8.87%). Fourteen cases were diagnosed as micro-invasive carcinoma (11.29%) and 4 cases as SCC (3.23%) The present study showed that most cases presented significant histological alterations, including epithelial dysplasia, micro-invasive carcinoma, and carcinoma, thus proving the importance of clinical and histological evaluations of actinic cheilitis.