MicroRNAs targeting peroxisome proliferator-activated receptor (PPAR) gene are differentially expressed in low birth weight placentae

Placenta(2023)

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摘要
•Lower mRNA expression of PPARα and PPARγ in LBW placentae.•Differential expression of miRNAs targeting PPAR in LBW placentae.•Maternal PUFAs and saturated fatty acids are associated with miRNA expression.•Placental omega-3 fatty acids are associated with miR-301a-5p.•Expression of differentially expressed miRNAs are associated with birth weight.
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关键词
Peroxisome proliferator-activated receptors, (PPARs), microRNA, Low birth weight, Placenta, Fatty acids
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