Geant4-DNA simulation of human cancer cells irradiation with helium ion beams

Physica Medica(2023)

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Abstract
•Using the Geant4-DNA toolkit to quantify early DNA damage from alpha particles.•Cancer cell lines HTB-177 and MCF-7 modelled with the “molecularDNA” example.•MC simulation of DNA damage with “molecularDNA” compared to experimental data.•Small differences between simulation and experiment for DNA double strand breaks.
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Key words
Geant4-DNA, MolecularDNA, Simulation, Cancer, Helium, Irradiation
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