Acute stimulation with symmetric biphasic pulses induces less ataxia compared to cathodic pulses in DBS for essential tremor

Alexandra Boogers,Jana Peeters, Tine Van Bogaert,Jan Rusz,Camelia Bogaert-Miclaus, Griet Loret,Philippe De Vloo,Wim Vandenberghe,Bart Nuttin,Myles Mc Laughlin

Parkinsonism & Related Disorders（2023）

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摘要

•When compared for 3 h, at supratherapeutic thresholds:•Biphasic pulses induce less stimulation-induced ataxia compared to cathodic pulses.•Biphasic pulses induce equivalent tremor control compared to cathodic pulses.•Diadochokinesis rate of speech was better for biphasic than cathodic pulses.

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