Functional characterization of IDUA variants identified by newborn screening

Molecular Genetics and Metabolism(2023)

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摘要
Optical fiber communication system is one of the core supporting systems of the modern internet age. For the simultaneous propagation of nonlinear waves in an inhomogeneous optical fiber, in this work, a coupled variable-coefficient fourth-order nonlinear Schrödinger system is studied. Infinitely-many conservation laws and N-fold Darboux transformation (DT) based on the existing Lax pair under certain constraints are derived, where N is a positive integer. Via the N-fold DT, the N-dark-bright soliton and Nth-order breather solutions under certain constraints are given. Interactions between the two dark-bright solitons are depicted graphically when the dispersion coefficient in that system, γ1(t), and the group velocity dispersion coefficient in that system, σ(t), are the constants and periodic functions, where t means the normalized retarded time. It is found that the velocities of the two dark-bright solitons increase as γ1(t) and σ(t) increase when γ1(t) and σ(t) are the constants. Interactions between the two breathers are presented graphically.
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关键词
idua variants,newborn screening
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