Tremor Reduction using DBS: Outcomes of a Real-world, Prospective, Multicenter Essential Tremor Registry

Essential Tremor (ET) is one of the most common neurological diseases affecting about 0.9% of the world population.1 ET treatment is focused on medical management of motor symptoms and includes pharmacotherapy and ventral intermediate nucleus (VIM) thalamotomy, which is being largely replaced by thalamic Deep Brain Stimulation (DBS) as the surgical treatment of choice. DBS of the VIM thalamus is recommended as a therapeutic option for appropriate subjects with ET.2 New insights regarding the real-world, clinical use of VIM DBS may be acquired through the implementation of large, multi-center patient registries. Here, we describe the initiation of a new ET patient registry for patients implanted with a multiple-source, constant- current DBS system capable of providing directionality for use in the management of Essential Tremor motor symptoms.