ID: 213353 Interim Analysis of ReActiv8-C: A Prospective Multi-Centre Registry of CLBP Patients Treated With Restorative Neurostimulation

Low back pain is the leading global cause of years lived with disability. Some cases recover with little intervention, some are amenable to surgical intervention, and some cases are intractable to current care paradigms. Restorative neurostimulation is a relatively new approach to intractable mechanical low back pain, that elicits an effect by long term direct stimulation of the medial branch of the dorsal ramus. This causes contraction of the multifidus muscle and to attempt to restore motor control and dynamic stability, improving pain and disability by a mechanism that accrues with continued use of the device. The two-year follow-up of from the IDE study demonstrated meaningful long-term improvements in this difficult to treat patient population.