Role of Hippocampal Wnt Signaling Pathways on Contextual Fear Memory Reconsolidation

Eduarda G. Nachtigall,Júlia D.R. de Freitas,Jociane de C. Myskiw,Cristiane R.G. Furini

Neuroscience（2023）

引用 4|浏览13

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摘要

•DKK1 infusion into the CA1 impaired the reconsolidation of contextual fear memory.•SFRP1 infusion into the CA1 had no effect on reconsolidation of contextual fear memory.•Wnt/β-catenin is necessary for CFC memory reconsolidation up to 2 h after reactivation.•There is a link between Wnt/β-catenin and NMDA receptors on CFC memory reconsolidation.

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