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Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody

Anna S. Efimova,Mariya A. Ustimova,Margarita A. Maksimova, Anastasya Yu. Frolova,Vladimir I. Martynov,Sergey M. Deyev,Alexey A. Pakhomov,Yurii V. Fedorov,Olga A. Fedorova

Mendeleev Communications（2023）

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Abstract
Two new styryl-type dyes modified with the succinimide ester group were prepared for conjugation with antibodies. The optical characteristics of the obtained compounds in different solvents were studied, and the solvatochromic properties of these dyes were revealed. The applicability of the dyes as protein labels was demonstrated in cyto-fluorometry and fluorescence microscopy.
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antibody,conjugates
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