Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease

Nikolaos Fountoulakis,Paraskevi-Maria Psefteli,Giuseppe Maltese,Luigi Gnudi,Richard C. Siow,Janaka Karalliedde

Kidney International Reports（2023）

引用 0|浏览4

暂无评分

摘要

In individuals with T2D and early DKD, lower levels of sKlotho are associated with increased Ao-PWV. Taken together with the direct effect of sKlotho on mediators of aortic wall stiffness , these findings may explain the enhanced risk of cardiorenal disease in DKD.

查看译文

关键词

arterial stiffness,diabetic kidney disease,soluble Klotho,type 2 diabetes mellitus

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要