Investigating the Interplay Between Gut Microbiome and Immune Landscape in Sarcoidosis

Sarcoidosis is a chronic systemic inflammatory disease characterized by granulomatous infiltration of affected organs, predominantly the lungs, with unclear etiology. Prior studies implicate microbial antigens as a trigger for inflammation driving granuloma formation. Considering potential cross-interactions along the lung-gut axis, we examine the relationship between gut microbiome and host immunity in sarcoidosis.