Cell lineage trees: the central structure plus key dynamics of biological aging and formulating the limiting problem of robust organismal rejuvenation

crossref(2019)

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摘要
The argument makes the case for cell lineage trees and cell tree dynamics to be considered as the central structure and process of understanding organismal level, multicellular biological aging. The upper limit challenge of counteracting biological aging is robust organismal rejuvenation. The limiting theoretical problem of robust biological rejuvenation is to find an algorithm to restore the balance and maintain the healthy dynamics of the aging organismal cell lineage tree. The most robust medical solution of biological aging needs to use individual cell lineage trees as a central tool for diagnosis and treatment.
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