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CD69 on Tumor-Infiltrating Cells Correlates With Neuroblastoma Suppression by Simultaneous PD-1 and PD-L1 Blockade

Seiichiro Inoue,Yuta Takeuchi,Yutaka Horiuchi,Takashi Murakami,Akio Odaka

Journal of Surgical Research（2023）

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Abstract
Our study confirms that lymphocytes are essential for the antitumor immune reaction induced by blocking PD-1/PD-L1 and raises the possibility that promoting the infiltration of activated CD8 TIL into tumors may be an effective treatment for neuroblastoma.
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Key words
neuroblastoma suppression,tumor-infiltrating
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