Morphological abnormalities in youth with bipolar disorder and their relationship to clinical characteristics.

Wenbin Li,Du Lei,Maxwell J Tallman,Jeffrey A Welge,Thomas J Blom,David E Fleck,Christina C Klein,Caleb M Adler,L Rodrigo Patino,Jeffrey R Strawn,Qiyong Gong,John A Sweeney,Melissa P DelBello

Journal of affective disorders（2023）

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摘要

Our findings indicate that youth with BD have significant neurostructural deficits in both cortical and subcortical regions mainly located in the regions related to emotion processing and regulation. Variability in clinical characteristics and comorbidities may contribute to the severity of anatomic alterations in this disorder.

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关键词

BD,ADHD,Psychotic symptoms,Structural MRI,Cortical thickness,Subcortical gray matter

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