Co-infection of Leishmania infantum and a Crithidia-related species in a case of refractory relapsed visceral leishmaniasis with non-ulcerated cutaneous manifestation in Brazil

Luana Aparecida Rogerio, Talita Yuri Takahashi, Luria Cardoso,Nayore Tamie Takamiya,Enaldo Vieira de Melo,Amelia Ribeiro de Jesus,Fabricia Alvisi de Oliveira,Sarah Forrester,Daniel C. Jeffares,João Santana da Silva, José Marcos Ribeiro,Roque Pacheco Almeida,Sandra Regina Maruyama

International Journal of Infectious Diseases（2023）

引用 3|浏览24

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摘要

•Severe visceral leishmaniasis with non-ulcerated cutaneous leishmaniasis.•A Crithidia-related parasite was isolated from bone marrow aspirate and spleen.•Whole-genome sequencing of clinical isolates suggested a novel parasite species.•Clinical implications of this trypanosomatid co-infection remain unknown in visceral leishmaniasis.

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关键词

Leishmania infantum, Crithidia sp, Trypanosomatid co-infection, Visceral leishmaniasis (VL), Non-ulcerated cutaneous leishmaniasis, (NUCL), Whole-genome sequencing analysis

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