Diversity of genetic platforms harboring the blaPER-2 gene in Enterobacterales and insights into the role of ISPa12 in its mobilization and dissemination

International Journal of Antimicrobial Agents(2023)

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摘要
•Eleven blaPER-2-harboring plasmids from Enterobacterales were fully sequenced.•The blaPER-2 gene was encoded on a variety of plasmid types (IncA, C, FIB, HI1B, N2).•ISPa12-composite transposons are suggested to be involved in blaPER-2 origin recruitment and dissemination.•A novel ISPa12-composite transposon, Tn7390, carrying the blaPER-2 gene was identified.•ISKox2-like elements seem to play a role in blaPER-2 gene dissemination.
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关键词
enterobacterales,ispa12,genetic,genetic
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