CD147 monoclonal antibody attenuates abdominal aortic aneurysm formation in angiotensin II-Infused apoE-/- mice

International Immunopharmacology(2023)

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摘要
•Our study demonstrated that the use of CD147 monoclonal antibody can effectively inhibit the formation of aneurysms.•The use of CD147 monoclonal antibody did not damage the liver and kidney function of mice.•CD147 may be a novel target in the treatment of abdominal aortic aneurysm.
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关键词
abdominal aortic aneurysm,abdominal aortic aneurysm formation,monoclonal antibody,ii-infused
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