Application and development of real-world study on Chinese patent medicine

Objective: This paper aims to summarize the development status and clinical application of Chinese patent medicine (CPM) in real-world study (RWS), and provide references for the use of real-world evidence (RWE) in the field of CPM. Methods: By searching keywords, we searched relevant literature in CNKI, Wanfang Data, PubMed and other databases, and summarized the application and development of RWS in CPM field. Results and conclusion: Currently, RWS has been frequently used in wide aspects of CPM field, mainly in observational study, including evaluation of effectiveness, safety and economics of CPM based on RWE. This paper reviews the applications above, which will help researchers to have an in-depth understanding of the development status and application characteristics of RWS in CPM field, and express views on the challenges and solutions facing the RWS of CPM, in order to guide and promote the development of the re-evaluation of CPM after marketing.