Cabernet sauvignon dry red wine ameliorates atherosclerosis in mice by regulating inflammation and endothelial function, activating AMPK phosphorylation, and modulating gut microbiota

Xinlong Cheng,Xue Han,Liangfu Zhou,Yasai Sun,Qian Zhou,Xuan Lin,Zhe Gao,Jie Wang,Wen Zhao

Food Research International（2023）

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摘要

•CSDRW treatment had potential anti-atherosclerotic effect in AS mouse model.•CSDRW treatment decreased the AS lesion size by 53.47% compared to AS mice.•CSDRW regulated the hepatic lipid metabolism pathway.•CSDRW regulated specific gut microbiota which were significantly correlated with AS.

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