Senescent adipocytes as potential effectors of muscle cells dysfunction: An in vitro model

Zoico Elena,Saatchi Tanaz,Nori Nicole,Mazzali Gloria,Rizzatti Vanni,Pizzi Eleonora,Fantin Francesco,Giani Anna,Urbani Silvia,Zamboni Mauro

Experimental Gerontology（2023）

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摘要

Recently, there has been a growing body of evidence showing a negative effect of the white adipose tissue (WAT) dysfunction on the skeletal muscle function and quality. However, little is known about the effects of senescent adipocytes on muscle cells.

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关键词

Aging, Adipose tissue, Skeletal muscle, Senescence, Myostatin

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