Intermodal correlation of quantitative CT-data and MRI-biomarkers derived from synchronous spectral CT-maps and breast MRI-examinations with molecular biomarkers in invasive ductal breast carcinomas

Konstantin Klein, Darius Gabriel Schafigh, Birgid Schömig-Markiefka,Graeme M. Campbell,Kilian Weiss,Wolfram Malter,David Maintz,Martin Hellmich,Kathrin Barbara Krug

European Journal of Radiology（2023）

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摘要

•The MRI parameters and DLCT parameters correlated with each other despite the time intervals between the examinations.•The iodine content and Zeffective numbers (DLCT) and the trends of the dynamic MRI curves correlated with immunohistochemical subtyping.•The T2w-signal intensities in the breast cancers normalized to those of the musculature correlated with immunohistochemical subtyping.

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关键词

Spectral computed tomography (CT), Chest CT, Dual-energy computed tomography (CT), breast MRI, biomarkers in breast cancer, Quantitative CT, MRI-texture analysis

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