Mitochondrial dysfunction in metabolic disorders induced by per- and polyfluoroalkyl substance mixtures in zebrafish larvae

•Exposure to the PFAS mixture reduces feed intake but increases energy expenditure.•Exposure to the PFAS mixture enhances glycolysis and β-oxidation, but inhibits phospholipid synthesis.•Exposure to the PFAS mixture disrupts glucose and lipid metabolism by affecting mitochondrial function.