323. Selectivity Analysis via Bayesian Reverse Inference Can Uncover Progressive Neuroanatomical Alteration in Schizophrenia

Jordi Manuello,Donato Liloia,Annachiara Crocetta, Francesca Dalla Mutta,Sergio Duca,Tommaso Costa,Franco Cauda

Biological Psychiatry（2023）

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摘要

We recently showed that an expanding pattern of morphological alteration can be detected during disease progression in Schizophrenia. Here we used the Bayes Factor to test whether brain regions involved in early phases are highly disorder-specific and therefore potentially considered as biomarkers.

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关键词

Schizophrenia, Meta-analysis, Voxel Based Morphometry, Biomarkers, Bayesian inference

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