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The association of HLA-DRB1 alleles and MBL2 gene variant in pediatric acute lymphoblastic leukemia patients

Rustu Oguz,Hayriye Senturk Ciftci,Muge Gokce,Yeliz Ogret,Sedat Karadeniz,Sacide Pehlivan,Kursat Ozdilli,Zeynep Karakas,Serap Karaman,Filiz Aydın

Hematology, transfusion and cell therapy（2023）

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Abstract
This is the first study suggesting that the MBL2 BB genotype in association with the DRB1*07 or co-inheritance of the HLA-DRB1*04 and HLA DRB1*07 may have an impact on the etiopathogenesis of the disease.
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Key words
Acute lymphoblastic leukemia,Mannose-binding lectin 2,Human leukocyte antigen,Polymorphism,Childhood leukemias
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