IRX1 is a novel gene, overexpressed in high-grade IDH-mutant astrocytomas.

Harsha S Sugur,Shilpa Rao,Palavalasa Sravya,K Athul Menon,Arimappamagan Arivazhagan,Bhupesh Mehta,Vani Santosh

Pathology, research and practice（2023）

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摘要

Our study identifies IRX1 as a novel biomarker overexpressed in high-grade IDH-mutant astrocytomas with prognostic significance in A3. DNMT3A mutation probably modulates IRX1 expression.

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关键词

IRX1,High-grade IDH-mutant astrocytoma,TCGA mRNA sequencing data,Nanostring,DNMT3A,Prognosis

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