Construction of magnetic MOF@COF hybrid via covalent integration for simultaneous identification of glyco‑ and phospho-proteins in human urine

Chemical Engineering Journal(2023)

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摘要
•A magnetic MOF@COF hybrid material was designed via covalent anchoring of MOF and COF.•The hybrid enables simultaneous enrichment of glyco- and phospho-proteins from urine without additional pretreatment steps.•The enrichment mechanism was validated by theoretical calculations.
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关键词
Magnetic MOF@COF Hybrid,Covalent Integration,Simultaneous Identification,Glyco‑ and Phospho-proteins,Urine
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