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NIR triggered photocatalytic and photothermal bifunctional MOF nanozyme using for improving osteoarthritis microenvironment by repairing injured chondrocytes of mitochondria

Shibo Xu,Yiyi Lin,Xingjun Zhao,Zepeng Liang,Yanan Hu,Zhenhua Chen,Xiuli Ren,Xifan Mei

Chemical Engineering Journal（2023）

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Abstract
•Photocatalytic and photothermal bifunctional nanozyme for treating osteoarthritis.•Gold-modified PCN hybrid nanozyme loaded with TP repairs damaged mitochondria.•The obtained materials promote cartilage regeneration and ameliorating joint wear.
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photothermal bifunctional mof nanozyme,osteoarthritis microenvironment,chondrocytes,mitochondria
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