27. Immediate-Early Genes ARC and c-Fos Show Divergent Brain-Wide Expression Patterns Following Contextual Fear Conditioning

Nicholas Bulthuis,Liliette Quintana, Michelle Stackmann,Christine Denny

Biological Psychiatry（2023）

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摘要

A neuronal engram is defined as the ensembled of cells in the brain that are active during both encoding and retrieval of a particular memory. These engrams are identifiable with immediate-early genes (IEGs), which are rapidly expressed upon neuronal activation, but the extent to which expression patterns are congruent between different IEGs is unclear.

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关键词

Contextual fear conditioning, Immediate early genes, Memory engrams, Basolateral amygdala, Hippocampus

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