35. Efficacy of Ketamine in Unmedicated Adults With OCD: A Randomized Controlled Trial
Biological Psychiatry(2023)
Abstract
We previously reported the rapid OCD symptom reduction of ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist, vs saline infusions in a proof-of-concept crossover trial (n=15) in unmedicated adults with OCD. Building on this initial finding, we evaluated the efficacy of ketamine in a larger group of unmedicated OCD patients with improved control conditions (active placebo control condition).
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Key words
Ketamine, Obsessive Compulsive Disorder (OCD), Mood/Anxiety
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