Immune cell subsets in patients with bipolar disorder or schizophrenia with history of childhood maltreatment

Brain, Behavior, and Immunity(2023)

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摘要
•Bipolar disorder and schizophrenia are associated with childhood maltreatment.•Bipolar disorder patients with childhood maltreatment exhibit high CD3 + CD8 + cytotoxic T lymphocyte levels and ow CD45RA+CCR7+CD8+ naïve CD8+ T cells.•Bipolar disorder patients with childhood maltreatment exhibit high CMV antibody levels.•BD cell subset profiles along CMV suggest cellular exhaustion/senescence.•SZ having experienced CM exhibit lower CD14+ monocyte levels.
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关键词
immune cell subsets,bipolar disorder,schizophrenia
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